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. My objective Using pandas, check a column for matching text not exact and update new column if TRUE. Data Manipulation using Pandas To understand this with an example lets create a new column called "NewAge" which contains the same value as Age column but with 5 added to it import pandas as pd Use The second argument is a column label, or a list of column labels, found in the second DataFrame (also postcode in this example. This solution is not particularly fast 1. colname.